Cysteine proteases in protozoan parasites.

Cysteine proteases (CPs) play key roles in the pathogenesis of protozoan ECUs parasites, including cell/tissue penetration, hydrolysis of host or parasite proteins, autophagy, and evasion or modulation of the host immune response, making them attractive chemotherapeutic and vaccine targets.This review highlights current knowledge on clan CA cystein

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Organ-at-risk sparing with dynamic trajectory radiotherapy for head and neck cancer: comparison with volumetric arc therapy on a publicly available library of cases

Abstract Background Dynamic trajectory radiotherapy (DTRT) extends volumetric modulated arc therapy Queen Panel Headboard (VMAT) with dynamic table and collimator rotation during beam-on.The aim of the study is to establish DTRT path-finding strategies, demonstrate deliverability and dosimetric accuracy and compare DTRT to state-of-the-art VMAT for

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